Thota Tharani's use of colours extends from a splash of bright hues to monochromatic shades which represent his unrestricted creativity. Some of his versatile creations stand tall at the Archives Municipals de Bordeaux, Ecole Des Beaux Arts Bordeaux, Tourism de l'Inde and Maison de l'Inde in Paris, France.
In India his art can be seen at Mitsubishi Corporation, Kolkata, ECC and Hindustan Motors, Chennai, Air India, Mumbai, National Gallery of Modern Art, Delhi, The Hindu, Chennai, ITC, Hyderabad, and the Grand Kakatiya, Hyderabad.
A creation by him was installed at UB City for the Opening of Art Bengaluru, the biggest Art Event in South India by Sublime Galleria. His series of paintings featuring Gods and Goddesses and Rajputs are very famous as well. His work consists of paintings, murals, paper collages, wooden montages, installations and so on.